ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2019, Vol. 50 ›› Issue (6): 1145-1153.doi: 10.11843/j.issn.0366-6964.2019.06.004

• ANIMAL GENETICS AND BREEDING • Previous Articles     Next Articles

Study on Genetic Diversity and Genetic Structure of Tibetan Sheep Populations

HU Liang1, SUN Wei1*, MA Yuehui2*   

  1. 1. College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China;
    2. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China
  • Received:2018-09-26 Online:2019-06-23 Published:2019-06-23

Abstract: This experiment was conducted to study population relationship of Tibetan sheep at the molecular level. A total of 384 individuals from 20 Tibetan sheep populations from 5 regions including Tibet, Qinghai, Gansu, Yunnan and Sichuan were selected for Affymetrix Ovine 600K chip scanning. The genetic diversity of Tibetan sheep populations was analyzed based on heterozygosity and inbreeding coefficient, and the population clustering of Tibetan sheep was analyzed by PCA, NJ-tree and STRUCTURE. The results showed that the observed heterozygosity of Tibet Langkazi sheep was the lowest (0.235 0) and the inbreeding coefficient was the highest (0.279 6). The observed heterozygosity of Qinghai valley type Tibetan sheep was the highest (0.323 4) and the inbreeding coefficient was the lowest (0.009 0). The results of genetic structure analysis showed that Tibetan sheep in Tibet and Yunnan could be gathered together alone, while grassland sheep in Qinghai, Gansu and Sichuan were clustered together in confusion. The results indicate that the genetic diversity of Tibetan sheep in Tibet and Yunnan is generally lower than that of Tibetan sheep in Qinghai, Gansu and Sichuan. Tibetan sheep in Tibet and Yunnan can maintain regional specificity, while grassland sheep in Qinghai, Gansu and Sichuan regions have little difference in genetic distance and population structure.

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